IPITA-IXA-CTRMS 2023

05:00-05:30

05:00
Hilton lobby area

Hilton lobby area

Congress Fun Run & Walk

Our Young Investigator Committee looks forward leading a run or walk in scenic San Diego! Sign up regardless of your fitness level, take part and enjoy a jog (or stroll).

Full Details

05:30-06:25

05:30
Indigo D

Indigo D

Encapsulation of cellular transplants 2

Full Details

Seon Mi Jang, Korea
Surface modification of alginate-based microcapsules using ethylamine-bridged EGCG dimer improves the structural stability of microcapsules and supports islet-xenograft survival

Craig Weber, United States
Effects of Hyperoxia on Human and Rat Islets

Trisha M Fabijanic, United States
The Development of a Sheep Model for Encapsulated Cell Therapies

Nicholas D Price, United States
Sustained hyperoxic exposure decreases cell viability and reduces cell growth in pancreatic beta cell lines

Olivia G Kelly, United States
Shielded Living Therapeutics platform for the treatment of type 1 diabetes

05:30-06:25

05:30
Indigo H

Indigo H

Islet Transplantation: Long-term outcomes

Full Details

Marie Christine Vantyghem, France
Twenty-year outcome after islet transplantation

Mohamed El-Shahawy, United States
Long-term insulin independence following allogenic islet transplant and childbirth

Rodolfo Alejandro, United States
Stable graft function and glycemic control 6 years after clinical islet transplantation on the omentum: A case report

David A. Baidal, United States
Insulin independence with excellent glycemic control at 17-years post-islet alone transplantation: A case report.

Mikael Chetboun, France
Relation between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective cohort study in 1210 participants from the Collaborative Islet Transplant Registry

06:30-07:30

06:30
Indigo D

Indigo D

CTRMS Business Meeting, 30th Anniversary & Awards Ceremony

Full Details

Klearchos K. Papas, United States
CTRMS Business Meeting

Klearchos K. Papas, United States
Scientific Congress Awards

Camillo Ricordi, United States
30 year history of CTRMS

06:30-07:30

06:30
Indigo A

Indigo A

Clinical Xenotransplantation: Are we there yet? (Join)

Full Details

Wayne J Hawthorne, Australia
History and ethics to get to clinical transplantation

Muhammad Mohiuddin, United States
First pig heart to human transplant

David D Bennett Jr., United States

Jayme Locke, United States
Pig kidney transplanted into deceased recipients

06:30-07:30

06:30
Indigo H

Indigo H

Total pancreatectomy and islet transplantation (IPITA)

Full Details

Melena Bellin, United States
Updated on Long-Term Outcomes of TPIAT

Ty B. Dunn, United States
Selecting the patient for TPIAT

Lorenzo Piemonti, Italy
Expanding the indications for TPIAT: Beyond Pancreatitis

07:30-08:00

07:30
Indigo D

Indigo D

CTRMS Ricordi Lecture

Supported by:

Full Details

Arnold I. Caplan, United States
Ricordi Lecture on MSCs are not Stem Cells

07:30-08:00

07:30
Foyer Area

Foyer Area

Coffee Break

Full Details

08:00-09:30

08:00
Indigo A

Indigo A

Islet transplantation: Novel therapies and novel methods

Full Details

Paul R.V. Johnson, United Kingdom
Perlecan: An islet basement membrane protein with anti-inflammatory qualities

Roberto Gramignoli, Sweden
Engineered pancreatic islets: Perinatal amnion epithelial cells in Support to pancreatic islet transplantation

ChaeRim Yoo, Korea
Hyperoxygeneration of chloroplast in hydrogel composed of alginate-peptide conjugate for successful pancreatic islet transplantation

Ge Li, United States
Functional subcutaneous engraftment of human islets achieved by co-transplantation with vasculogenic and adaptable endothelial cells

Yi Wang, People's Republic of China
Prolactin modulates the differentiation of pancreatic ductal cell to islet-like cell

Keiko Omori, United States
Gastrin-17 promotes survival and function and decreases inflammation of long-term cultured human islets

Karim Bouzakri, France
ILV-001 a highly promising therapeutic agent for islet transplantation

Simon N Chu, United States
Improving the safety of stem-cell-derived beta cell transplantation with an inducible safety switch

Bashoo Naziruddin, United States
Expansion and Differentiation of Human Pancreas-derived Islet Cell Precursors into Functional Islet Cell Organoids

08:00-09:30

08:00
Indigo D

Indigo D

Stem cell and stem cell-derived / Cell biology and regeneration 2

Full Details

Adriana Migliorini, Canada
Deciphering the hematopoietic pancreatic niche during human fetal development

William Rust, United States
Novel stem cell-derived islet-like clusters potently control rodent blood glycemia

Daniel Norman, Sweden
Function and composition of SC-derived islets transplanted to multiple organ sites show the highest function in liver

Yuki Y Imaoka, United States
Preserving Liver Natural Killer Cell Activity: Developing Novel Culture Techniques for "Off-the-Shelf" Cell Immunotherapy

Lorelei Hughes, United States
Prostaglandin E2 Induces YAP1 and Agrin via EP4 in Islet-1+ Stem Cells that Improve Cardiac Repair in a Sheep Model of Myocardial Infarction

Chika Takano, Japan
Single-cell transcriptomes reveal phylogenetic diversification of human amniotic epithelial cells

Quentin Perrier, France
Effect of photobiomodulation on the viability and functionality of islet cells and pancreatic islet in vitro

Quentin Perrier, France
Belatacept, Tacrolimus effect on beta cells viability and insulin secretion

Anjali Verma, United States
Enhancing mesenchymal stem cell’s intrinsic expression of MMP-9 to augment their anti-fibrotic capacities for the treatment of liver diseases

08:00-09:30

08:00
Indigo H

Indigo H

Monitoring pre-clinical and clinical application of xenotransplantation

Full Details

Ahmad Karadagi, United States
Long-term (2 years) survival of porcine to nonhuman primate life-sustaining kidney xenotransplantation

David K Cooper, United States
Are xenotransplantation experiments in brain-dead human subjects (decedents), justified?

Merle Flecks, Germany
Analysis of PERV-C superinfection resistance using HA-tagged viruses

Yu Hisadome, United States
Routine cold storage (5 hours) leads to hyperacute graft loss in pig-to-primate kidney xenotransplantation; hypothermic machine perfusion may be preferred preservation modality

Joachim Denner, Germany
Effective detection and elimination strategies for porcine viruses

Massimo Mangiola, United States
Anti-pig Antibodies in Human Immunoglobulin Preparations

Heiner Niemann, Germany
Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo-glycans

Tianshu Zhang, United States
Anti-pig antibodies monitoring In The First Cardiac Xenotransplantation From Genetically Engineered Pig to a Human

Andrew Tully, United States
Immune Monitoring of The First Cardiac Xenotransplant From Genetically engineered pig to a Human

09:35-10:35

09:35
Indigo BC

Indigo BC

Keynote Lecture and Closing Address

Full Details

Jeff W.M. Bulte, United States
Preclinical and clinical Non-Invasive Cellular Imaging

Wayne J Hawthorne, Australia
eGenesis travel scientific awards

Raja Kandaswamy, United States
Closing address from Congress chair

Thomas W.H. Kay, Australia
Presentation of IPITA 2025

Muhammad Mohiuddin, United States
Presentation of IXA 2025

Toshio Miki, Japan
Presentation of CTRMS 2025

05:30 - 06:25 | Oral Abstract Sessions

06:30 - 07:45 | Concurrent Sessions

07:30 - 08:00 | Ricordi Lecture / Coffee Break

08:00 - 09:30 | Oral Abstract Sessions

09:35 - 10:35 | Keynote and Closing Address

Organized by

Supported by

Hosted by

Time	Room	Session
05:00-05:30	05:00 Hilton lobby area	Hilton lobby area	Congress Fun Run & Walk Our Young Investigator Committee looks forward leading a run or walk in scenic San Diego! Sign up regardless of your fitness level, take part and enjoy a jog (or stroll). Full Details
05:30 - 06:25 \| Oral Abstract Sessions
05:30-06:25	05:30 Indigo D	Indigo D	Encapsulation of cellular transplants 2 Full Details Seon Mi Jang, Korea Surface modification of alginate-based microcapsules using ethylamine-bridged EGCG dimer improves the structural stability of microcapsules and supports islet-xenograft survival Seon Mi Jang, Korea Surface modification of alginate-based microcapsules using ethylamine-bridged EGCG dimer improves the structural stability of microcapsules and supports islet-xenograft survival Craig Weber, United States Effects of Hyperoxia on Human and Rat Islets Craig Weber, United States Effects of Hyperoxia on Human and Rat Islets Trisha M Fabijanic, United States The Development of a Sheep Model for Encapsulated Cell Therapies Trisha M Fabijanic, United States The Development of a Sheep Model for Encapsulated Cell Therapies Nicholas D Price, United States Sustained hyperoxic exposure decreases cell viability and reduces cell growth in pancreatic beta cell lines Nicholas D Price, United States Sustained hyperoxic exposure decreases cell viability and reduces cell growth in pancreatic beta cell lines Olivia G Kelly, United States Shielded Living Therapeutics platform for the treatment of type 1 diabetes Olivia G Kelly, United States Shielded Living Therapeutics platform for the treatment of type 1 diabetes
05:30-06:25	05:30 Indigo H	Indigo H	Islet Transplantation: Long-term outcomes Full Details Marie Christine Vantyghem, France Twenty-year outcome after islet transplantation Marie Christine Vantyghem, France Twenty-year outcome after islet transplantation Mohamed El-Shahawy, United States Long-term insulin independence following allogenic islet transplant and childbirth Mohamed El-Shahawy, United States Long-term insulin independence following allogenic islet transplant and childbirth Rodolfo Alejandro, United States Stable graft function and glycemic control 6 years after clinical islet transplantation on the omentum: A case report Rodolfo Alejandro, United States Stable graft function and glycemic control 6 years after clinical islet transplantation on the omentum: A case report David A. Baidal, United States Insulin independence with excellent glycemic control at 17-years post-islet alone transplantation: A case report. David A. Baidal, United States Insulin independence with excellent glycemic control at 17-years post-islet alone transplantation: A case report. Mikael Chetboun, France Relation between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective cohort study in 1210 participants from the Collaborative Islet Transplant Registry Mikael Chetboun, France Relation between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective cohort study in 1210 participants from the Collaborative Islet Transplant Registry
06:30 - 07:45 \| Concurrent Sessions
06:30-07:30	06:30 Indigo D	Indigo D	CTRMS Business Meeting, 30th Anniversary & Awards Ceremony Full Details Klearchos K. Papas, United States CTRMS Business Meeting Klearchos K. Papas, United States CTRMS Business Meeting Klearchos K. Papas, United States Scientific Congress Awards Klearchos K. Papas, United States Scientific Congress Awards Camillo Ricordi, United States 30 year history of CTRMS Camillo Ricordi, United States 30 year history of CTRMS
06:30-07:30	06:30 Indigo A	Indigo A	Clinical Xenotransplantation: Are we there yet? (Join) Full Details Wayne J Hawthorne, Australia History and ethics to get to clinical transplantation Wayne J Hawthorne, Australia History and ethics to get to clinical transplantation Muhammad Mohiuddin, United States First pig heart to human transplant Muhammad Mohiuddin, United States First pig heart to human transplant David D Bennett Jr., United States David D Bennett Jr., United States Jayme Locke, United States Pig kidney transplanted into deceased recipients Jayme Locke, United States Pig kidney transplanted into deceased recipients
06:30-07:30	06:30 Indigo H	Indigo H	Total pancreatectomy and islet transplantation (IPITA) Full Details Melena Bellin, United States Updated on Long-Term Outcomes of TPIAT Melena Bellin, United States Updated on Long-Term Outcomes of TPIAT Ty B. Dunn, United States Selecting the patient for TPIAT Ty B. Dunn, United States Selecting the patient for TPIAT Lorenzo Piemonti, Italy Expanding the indications for TPIAT: Beyond Pancreatitis Lorenzo Piemonti, Italy Expanding the indications for TPIAT: Beyond Pancreatitis
07:30 - 08:00 \| Ricordi Lecture / Coffee Break
07:30-08:00	07:30 Indigo D	Indigo D	CTRMS Ricordi Lecture Supported by: Full Details Arnold I. Caplan, United States Ricordi Lecture on MSCs are not Stem Cells Arnold I. Caplan, United States Ricordi Lecture on MSCs are not Stem Cells
07:30-08:00	07:30 Foyer Area	Foyer Area	Coffee Break Full Details
08:00 - 09:30 \| Oral Abstract Sessions
08:00-09:30	08:00 Indigo A	Indigo A	Islet transplantation: Novel therapies and novel methods Full Details Paul R.V. Johnson, United Kingdom Perlecan: An islet basement membrane protein with anti-inflammatory qualities Paul R.V. Johnson, United Kingdom Perlecan: An islet basement membrane protein with anti-inflammatory qualities Roberto Gramignoli, Sweden Engineered pancreatic islets: Perinatal amnion epithelial cells in Support to pancreatic islet transplantation Roberto Gramignoli, Sweden Engineered pancreatic islets: Perinatal amnion epithelial cells in Support to pancreatic islet transplantation ChaeRim Yoo, Korea Hyperoxygeneration of chloroplast in hydrogel composed of alginate-peptide conjugate for successful pancreatic islet transplantation ChaeRim Yoo, Korea Hyperoxygeneration of chloroplast in hydrogel composed of alginate-peptide conjugate for successful pancreatic islet transplantation Ge Li, United States Functional subcutaneous engraftment of human islets achieved by co-transplantation with vasculogenic and adaptable endothelial cells Ge Li, United States Functional subcutaneous engraftment of human islets achieved by co-transplantation with vasculogenic and adaptable endothelial cells Yi Wang, People's Republic of China Prolactin modulates the differentiation of pancreatic ductal cell to islet-like cell Yi Wang, People's Republic of China Prolactin modulates the differentiation of pancreatic ductal cell to islet-like cell Keiko Omori, United States Gastrin-17 promotes survival and function and decreases inflammation of long-term cultured human islets Keiko Omori, United States Gastrin-17 promotes survival and function and decreases inflammation of long-term cultured human islets Karim Bouzakri, France ILV-001 a highly promising therapeutic agent for islet transplantation Karim Bouzakri, France ILV-001 a highly promising therapeutic agent for islet transplantation Simon N Chu, United States Improving the safety of stem-cell-derived beta cell transplantation with an inducible safety switch Simon N Chu, United States Improving the safety of stem-cell-derived beta cell transplantation with an inducible safety switch Bashoo Naziruddin, United States Expansion and Differentiation of Human Pancreas-derived Islet Cell Precursors into Functional Islet Cell Organoids Bashoo Naziruddin, United States Expansion and Differentiation of Human Pancreas-derived Islet Cell Precursors into Functional Islet Cell Organoids
08:00-09:30	08:00 Indigo D	Indigo D	Stem cell and stem cell-derived / Cell biology and regeneration 2 Full Details Adriana Migliorini, Canada Deciphering the hematopoietic pancreatic niche during human fetal development Adriana Migliorini, Canada Deciphering the hematopoietic pancreatic niche during human fetal development William Rust, United States Novel stem cell-derived islet-like clusters potently control rodent blood glycemia William Rust, United States Novel stem cell-derived islet-like clusters potently control rodent blood glycemia Daniel Norman, Sweden Function and composition of SC-derived islets transplanted to multiple organ sites show the highest function in liver Daniel Norman, Sweden Function and composition of SC-derived islets transplanted to multiple organ sites show the highest function in liver Yuki Y Imaoka, United States Preserving Liver Natural Killer Cell Activity: Developing Novel Culture Techniques for "Off-the-Shelf" Cell Immunotherapy Yuki Y Imaoka, United States Preserving Liver Natural Killer Cell Activity: Developing Novel Culture Techniques for "Off-the-Shelf" Cell Immunotherapy Lorelei Hughes, United States Prostaglandin E2 Induces YAP1 and Agrin via EP4 in Islet-1+ Stem Cells that Improve Cardiac Repair in a Sheep Model of Myocardial Infarction Lorelei Hughes, United States Prostaglandin E2 Induces YAP1 and Agrin via EP4 in Islet-1+ Stem Cells that Improve Cardiac Repair in a Sheep Model of Myocardial Infarction Chika Takano, Japan Single-cell transcriptomes reveal phylogenetic diversification of human amniotic epithelial cells Chika Takano, Japan Single-cell transcriptomes reveal phylogenetic diversification of human amniotic epithelial cells Quentin Perrier, France Effect of photobiomodulation on the viability and functionality of islet cells and pancreatic islet in vitro Quentin Perrier, France Effect of photobiomodulation on the viability and functionality of islet cells and pancreatic islet in vitro Quentin Perrier, France Belatacept, Tacrolimus effect on beta cells viability and insulin secretion Quentin Perrier, France Belatacept, Tacrolimus effect on beta cells viability and insulin secretion Anjali Verma, United States Enhancing mesenchymal stem cell’s intrinsic expression of MMP-9 to augment their anti-fibrotic capacities for the treatment of liver diseases Anjali Verma, United States Enhancing mesenchymal stem cell’s intrinsic expression of MMP-9 to augment their anti-fibrotic capacities for the treatment of liver diseases
08:00-09:30	08:00 Indigo H	Indigo H	Monitoring pre-clinical and clinical application of xenotransplantation Full Details Ahmad Karadagi, United States Long-term (2 years) survival of porcine to nonhuman primate life-sustaining kidney xenotransplantation Ahmad Karadagi, United States Long-term (2 years) survival of porcine to nonhuman primate life-sustaining kidney xenotransplantation David K Cooper, United States Are xenotransplantation experiments in brain-dead human subjects (decedents), justified? David K Cooper, United States Are xenotransplantation experiments in brain-dead human subjects (decedents), justified? Merle Flecks, Germany Analysis of PERV-C superinfection resistance using HA-tagged viruses Merle Flecks, Germany Analysis of PERV-C superinfection resistance using HA-tagged viruses Yu Hisadome, United States Routine cold storage (5 hours) leads to hyperacute graft loss in pig-to-primate kidney xenotransplantation; hypothermic machine perfusion may be preferred preservation modality Yu Hisadome, United States Routine cold storage (5 hours) leads to hyperacute graft loss in pig-to-primate kidney xenotransplantation; hypothermic machine perfusion may be preferred preservation modality Joachim Denner, Germany Effective detection and elimination strategies for porcine viruses Joachim Denner, Germany Effective detection and elimination strategies for porcine viruses Massimo Mangiola, United States Anti-pig Antibodies in Human Immunoglobulin Preparations Massimo Mangiola, United States Anti-pig Antibodies in Human Immunoglobulin Preparations Heiner Niemann, Germany Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo-glycans Heiner Niemann, Germany Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo-glycans Tianshu Zhang, United States Anti-pig antibodies monitoring In The First Cardiac Xenotransplantation From Genetically Engineered Pig to a Human Tianshu Zhang, United States Anti-pig antibodies monitoring In The First Cardiac Xenotransplantation From Genetically Engineered Pig to a Human Andrew Tully, United States Immune Monitoring of The First Cardiac Xenotransplant From Genetically engineered pig to a Human Andrew Tully, United States Immune Monitoring of The First Cardiac Xenotransplant From Genetically engineered pig to a Human
09:35 - 10:35 \| Keynote and Closing Address
09:35-10:35	09:35 Indigo BC	Indigo BC	Keynote Lecture and Closing Address Full Details Jeff W.M. Bulte, United States Preclinical and clinical Non-Invasive Cellular Imaging Jeff W.M. Bulte, United States Preclinical and clinical Non-Invasive Cellular Imaging Wayne J Hawthorne, Australia eGenesis travel scientific awards Wayne J Hawthorne, Australia eGenesis travel scientific awards Raja Kandaswamy, United States Closing address from Congress chair Raja Kandaswamy, United States Closing address from Congress chair Thomas W.H. Kay, Australia Presentation of IPITA 2025 Thomas W.H. Kay, Australia Presentation of IPITA 2025 Muhammad Mohiuddin, United States Presentation of IXA 2025 Muhammad Mohiuddin, United States Presentation of IXA 2025 Toshio Miki, Japan Presentation of CTRMS 2025 Toshio Miki, Japan Presentation of CTRMS 2025